Abstract

Abstract Twenty-nine female rats were utilized to study the effects of various diencephalic lesions on motor activity as well as recovery from aphagia. Animals were administered four separate tests to assess relative degrees of hypokinesis as compared to operated and non-operated controls: open field activity, step-down latencies, waxy flexibility, and stabilization in a horizontal plane. All lesioned rats displayed moderate to high degrees of aphagia and were distinctly inferior to controls on all tests of activity. Variations in behavior appeared as a function of antero-posterior and medio-lateral loci of the lesions in the diencephalon. The data were discussed with regard to previous results concerning the importance of motivational versus motor components in aphagia. A dissociation between food intake and hypokinesis was arrived at on the basis of behavioral and neuroanatomical findings.

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