Abstract
In an earlier paper we reported that isologous as well as heterologous deoxyribonucleic acid (DNA) increases the survival of X-irradiated L-cells grown in culture (1). These results indicate that DNA precursors, such as oligonucleotides, nucleotides, and nucleosides, may be of considerable importance in restoration, and that the addition of DNA molecules in their highly polymerized form is not the main condition for successful restoration of lethally damaged cells. A number of experiments with enzymatically hydrolyzed DNA and commercial deoxyribonucleotides were carried on to establish their action on the damaged proliferative capacity of the X-irradiated L-cells.
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