Abstract
Background: Sodium hypochlorite is a denture cleaning solution that is widely used as an efficient cleaning method. However, it has disadvantages of uncomfortable taste and smell. Therefore, therapeutic plant extracts are safer for the human body, they are used as an alternative for denture cleaning agents. Objective: To analyze the effect of act-ive compounds extracted from therapeutic plants in inhibiting the growth of Candida albicans. Methods: Ten selected articles were obtained from five search engines with due observance of PICO and specified inclusion criteria, then an assessment was carried out on ten selected articles which were assessed based on the assessment criteria of The Joanna Briggs Institute Criticial Appraisal Tools checklist and deserved to be included in writing a systematic review. Results: The plant extracts from ten articles were lemongrass extract and cinnamon extract, which were fungistatic and fungicidal; while the extracts of black cumin, mangrove leaf, rosella flower, ketapang leaf, mexico tea, and grape seed were fungistatic only. Conclusion: The active compounds of the terpenoid and phenolic groups from had ade-quate antifungal activity, but the active compounds in the phenolic group had lower antifungal activity due to the withdrawal of chlorophyl and carotenoid pigments which are known have antioxidants and antifungal properties.
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