The effect of DAG oil replacing TAG oil on weight control and glycolipid metabolism: A meta-analysis of randomized controlled trials

Abstract

• DAG oil intake reduces body weight and body mass index in healthy people. • Intake of DAG oil has a specific effect on reducing WC and serum TC. • The duration of eating DAG oil is significantly related to the effect of weight loss. • The longer the intake of DAG oil, the better the weight loss effect. The primary objective of this study is to summarize the effect of diacylglycerol (DAG) oil consumption on weight loss, glucose and lipid metabolism. The weighted mean difference (WMD) with 95% CI’s was calculated using the generic inverse variance approach. Heterogeneity was assessed and analyzed using the Cochran Q-statistic. In the overall analysis, intake of DAG oil can significantly reduce body weight (BW), body mass index (BMI), waist circumference (WC) in healthy people, and serum triacylglycerol (TAG) in people with diseases related to glucose and lipid metabolism, but has no significant effect on blood glucose (BG). Meta-regression analysis based on duration of intervention was significant for BW, BMI, and WC. The longer the intake of DAG oil, the better the weight loss effect. Pooled analyses show that DAG oil consumption has health advantages in maintaining a healthy weight, BMI, WC, serum TAG, and BG levels.