Abstract
This study was conducted to determine the effect of ethanol extract of curry leaves ( Murraya koenigii L.) on blood glucose levels in alloxan diabetic mice ( Mus musculus ). The diabetic conditions were made by giving alloxan 75 mg/kg body weight (BW) and the hypoglycemic effects of extract of curry leaves given with various doses. This study used 24 male mice strain Balb/c in four groups of treatment with six replications, namely the negative control group, the ethanol extract of curry leaf tree 50% mL/10g body weight group, 70% mL/10g body weight group and 90% mL/10g body weight group. The treatment was given orally by using a gastric sonde for 14 days. Blood samples were taken through the sinus caudalis using a scissors. Blood glucose level was measured at 1st , the 8th and the 24th of treatment using blood glucose test strips and Nesco® Multicheck apparatus. Blood glucose data were analyzed by one way ANOVA (Analysis of Variants) and followed by Tuckey test at significance level of 5%. The result showed that treatment of ethanol extract of curry leaves ( Murraya koenigii ) at various doses significantly affected the decrease on blood glucose levels of mice ( Mus musculus ) alloxan diabetic.
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