Abstract
The effects of different sources of colony-stimulating factor (CSF) and of cryopreservation have been studied on committed stem cells (CFU-c's) in bone marrow aspirates from patients with nonhematological ailments, acute leukemia (AL) in remission, and solid tumors, and in peripheral blood from patients with chronic myeloid leukemia (CML). Results showed significant effects due to the source of CSF and to freezing, colony scores being reduced on human placental-conditioned medium (HPCM) after freezing, whereas they remained the same or were increased on peripheral leukocyte underlayers (PBU). An analysis of the differential morphology of the CFU-c's showed that the ratio of eosinophil to polymor-phonuclear colonies was significantly lower on HPCM and after freezing on both sources of CSF.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
