Abstract
In patients with rhinosinusitis polyposa, activation of type 2 eosinophilic inflammation with an increase in serum concentrations of interleukins 4, 5, and 13 and immunoglobulins A, M, G, and E is noted. At the same time, the relationship between these indicators and the quality of life of the patient is sharply intensified, which indicates the appearance of pathological correlation pleiades. The drug Dupilumab has a normalizing effect on the inflammatory component of the disease and optimizes the cytokine regulation of humoral immunity. The additional use of an alternating magnetic field somewhat enhances these effects, whereas the maximum therapeutic effect was provided by the use of the drug, an alternating magnetic field, and low‑intensity infrared laser therapy.
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