Abstract
Hyperglycemia in people with diabetes mellitus causes oxidative stress which can interfere with the provision of nutrients through blood vessels to the tissues that form spermatozoa so that it interferes with the process of spermatogenesis in the testicular organs. Coffee contains caffeine and chlorogenic acid which functions as an antioxidant to improve spermatogenesis abnormalities which causes decreased number of normal spermatozoa. The purpose of this study was to determine the ability of coffee in improving the number of spermatozoa of alloxan induced wistar white rats.. Methods this study uses Post-test only laboratory experimental research with control group design. Submitting 30 rats divided into 5 groups: normal control (given aquades), negative control (induced alloxan + aquades), setting 1 (induced alloxan + coffee 0.054 gram / 200 gramBB), aid 2 (alloxan induced + coffee 0.108 gram / 200 gramBB ) and treatment 3 (alloxan + coffee induced 0.162 gram / 200 gramBB). Provision of coffee carried out for 14 days, rats terminated on the 15th day. Testicles are taken then observed and counted spermatozoa. One-way ANOVA test results show the value of p = 0.000. In the LSD test between the normal control group (aquades) and negative control (diabetic rats without treatment) had a value of p = 0.042, whereas in the treatment group 1.2.3 with a negative control had a value of p = 0.000. Provision of coffee can increase the number of spermatozoa white wistar strain alloxan induced.
Highlights
Hiperglikemi pada penderita diabetes melitus mengakibatkan stres oksidatif yang dapat menganggu pemberian nutrisi melalui pembuluh darah ke jaringan-jaringan pembentuk spermatozoa sehingga menganggu proses spermatogenesis pada organ testis
causes oxidative stress which can interfere with the provision of nutrients
so that it interferes with the process of spermatogenesis
Summary
Hiperglikemi pada penderita diabetes melitus mengakibatkan stres oksidatif yang dapat menganggu pemberian nutrisi melalui pembuluh darah ke jaringan-jaringan pembentuk spermatozoa sehingga menganggu proses spermatogenesis pada organ testis. Kopi mengandung kafein dan asam klorogenat yang berfungsi sebagai antioksidan sehingga dapat memperbaiki abnormalitas spermatogenesis yang menyebabkan penurunan jumlah spermatozoa normal. Tujuan penelitian ini untuk mengetahui kemampuan kopi dalam memperbaiki jumlah spermatozoa tikus putih galur wistar yang diinduksi aloksan.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
