Abstract
Magnesium (Mg)-based composites, as one group of the biodegradable materials, enjoy high biodegradability, biocompatibility, and non-toxicity making them a great option for implant applications. In this paper, by the semi powder metallurgy (SPM) technique, the graphene nano-platelets (GNPs) and carbon nanotubes (CNTs) nanosystems, as reinforcements, are dispersed homogenously in the Mg–Zn (MZ) alloy matrix. Subsequently, the composite is successfully produced employing the spark plasma sintering (SPS) process. Compared to the unreinforced MZ sample, GNPs + CNTs mixture reinforced composite exhibits higher compressive strength (∼75%). Notably, adding only 1 wt % of GNPs + CNTs to the MZ matrix reduces the rate of the degradation in the Mg-based composite by almost 2- fold. Examining the antibacterial activity demonstrate that the incorporation of GNPs + CNTs into the Mg-based matrix is likely to prevent the infiltration and development of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) significantly. While the MTT with 0.5 and 1 wt % GNPs + CNTs does not demonstrate cytotoxicity to the MG63 cells, the excessive GNPs + CNTs results in a certain degree of poisonousness. In general, the findings of the present research attest to the viable application of MZ/GNPs + CNTs composites for implants as well as bone infection treatment.
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More From: Journal of the Mechanical Behavior of Biomedical Materials
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