Abstract

Studies were conducted on the effect of clomiphene on ovulation and spawning in mature C. carpio pre‐treated with indomethacin. It was demonstrated that indomethacin caused a block to ovulation and spawning at two dose levels (5 and 10 μg−1g). This blockade could be overcome by two (10 μg−1g each) successive dosages of clomiphene given 7 and 31 h after the indomethacin treatment. When indomethacin and clomiphene treatments were given concomittantly, the inhibitory effects of indomethacin remained more pronounced.

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