Abstract

Succinic acid can just as well be replaced by citric acid in submerged fermentation of lysergic acid derivatives by a strain of Claviceps paspali. The highest alkaloid yields were obtained with a 1% citric acid concentration in the medium at a constant pH of 5.2. When the optimal pH was not maintained, growth was inhibited and all aspects of metabolic activity of the fungus were depressed.

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