Abstract
The intravenous administration of amikacin was studied during 61 courses of therapy in 40 infants who had a mean birth weight of 1,210 gm. A dose of 7.5 mg/kg of amikacin administered intravenously over one hour every 12 hours consistently produced peak blood concentrations within the therapeutic range during the first two weeks of life. As chronologic age increased beyond the second week of life, mean peak and trough amikacin blood concentrations progressively decreased. At CA≤14 days, 15 to 28 days, and ≥29 days mean peak amikacin blood values were 22.3, 21.4, and 19.8 μg/ml, respectively. The percentage of infants in each of these three age groups having at least one peak concentration
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
