Abstract
The Effect of Chronic Pancreatitis on Portal Venous Velocities
Highlights
Portal vein thrombosis in case of chronic pancreatitis can be induced by several interacting factors: local prothrombotic factors, endothelial damage in case of repeated acute inflammation, mechanical pressure and relatively slower venous velocities
Vmax and Vmean were slower in case of chronic pancreatitis, but the difference was not significant: 59 ± 24,2 cm/s vs 67,5 ± 21 cm/s in healthy controls (p=0,554); and 20,8 ± 7,7 cm/s vs 24,5 ± 8,2 cm/s (p=0,322) respectively
Chronic pancreatitis has no effect on portal venous velocities
Summary
Portal vein thrombosis in case of chronic pancreatitis can be induced by several interacting factors: local prothrombotic factors, endothelial damage in case of repeated acute inflammation, mechanical pressure and relatively slower venous velocities. Our aim was to assess whether chronic pancreatitis has any effect on portal vein velocities. The incidence of CP, according to various studies, varies from 4,4 to 13,4 per 100 000 and the prevalence ranges from 36,9 to 41,8 cases per 100 000 [5,6,7,8,9,10,11,12,13,14,15]. Portal vein thrombosis (PVT), being the most common vascular disorder of the liver, is in 40% of cases associated with local factors, pancreatitis being one of them. Pancreatitis is not very common cause of PVT, only about 13% of PVT cases are associated with pancreatitis in general [16]
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