Abstract
The effect of methionine deficiency on the metabolic fate of cyanocobalamin in rats was studied. No significant differences in the absorption and excretion of orally administered 60Co-labeled cyanocobalamin were noted between methionine-deficient and methionine-supplemented groups. The retention of injected 60Co-labeled cyanocobalamin by the kidney, liver, spleen and heart of methionine-deficient rats was higher than that of methionine-supplemented rats. These results suggest that there may be an increase in the utilization of vitamin B 12 to ameliorate methionine deficiency by sparing methyl group and/or by increasing methionine synthesis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
