Abstract
The effect of chlorpromazine on the contents of dopamine in rat's brains has been studied in order to clarify the cause of the chlorpromazine-induced Parkinsonism. A significant reduction of the contents of dopamine and also noradrenaline in rat's brains was noted one hour after a single i. p. injection of chlorpromazine. The significance of this result was discussed in connection with the therapeutic effect of L-dopa on the pharmacological Parkinsonism.
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