The Effect of Changing Positive End-Expiratory Pressures on the Spatial Pattern of Lung Ventilation in Newborn Rabbits Ventilated from Birth

Abstract

Background: Positive end-expiratory pressure (PEEP) helps very preterm newborns develop functional residual capacity (FRC) and establish adequate gas exchange at birth. In the immediate newborn period, lungs commonly experience changes in PEEP, particularly when the face mask is removed and replaced. This study aimed to determine the distribution of lung ventilation at different PEEPs and in response to changes in PEEP.