Abstract

Purpose: We investigated the effect of menstrual cycle on the cardiovascular responses during recovery period from exercise. 10 healthy women were participated in the early follicular phase (EP: low estrogen and low progesterone: 1 - 4 days) and the late follicular phase (LP: high estrogen and low progesterone: 10 - 13 days) during menstrual cycle. Methods: All subjects completed a graded cycling exercise testing to determine the relative exercise intensity. All subjects were assessed systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), stroke volume (SV), cardiac output (CO), and total vascular conductance (TVC) at resting and during recovery period from moderated cycling exercise during EP and LP. Results: During EP, compared with LP, resting SBP and MAP were higher and TVC was lower (p < 0.05). During recovery from exercise, SBP and MAP were higher and TVC lower during EP compared with LP (p < 0.05). There were no differences in HR, SV and CO in both phases. Conclusions: This study could be increased the peripheral vasoconstriction in low estrogen levels. And during early follicular phase with low estrogen level, it may maintain an increased blood pressure during recovery period following cycling. We suggest that the timing of the menstrual cycle should be considered when measuring blood pressure during clinical exercise testing.

Highlights

  • We investigated the effect of menstrual cycle on the cardiovascular responses during recovery period from exercise. 10 healthy women were participated in the early follicular phase (EP: low estrogen and low progesterone: 1 - 4 days) and the late follicular phase (LP: high estrogen and low progesterone: 10 - 13 days) during menstrual cycle

  • Menopause intensifies the risk of cardiovascular disease drastically in women compared with men of the same age by increasing low-density lipoprotein cholesterol (LDLC) levels and blood pressure [1]

  • systolic blood pressure (SBP) and mean arterial pressure (MAP) at rest and during exercise were higher during the LP compared to the EP (p < 0.05)

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Summary

Introduction

Menopause intensifies the risk of cardiovascular disease drastically in women compared with men of the same age by increasing low-density lipoprotein cholesterol (LDLC) levels and blood pressure [1]. For this reason, measures have been devised. Park et al 426 in attempts to improve and prevent cardiovascular disease in women, and of these, participation in physical activity is the most effective and recommended option [2] Both estrogen and progesterone levels are at their lowest during menstruation, while the level of estrogen secretion increases in the ovulatory phase and estrogen levels drop as progesterone levels rise after ovulation [3]. A difference in response to exercise can be induced during the menstrual cycle with estrogen level changes in women before menopause [6]

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