The effect of carbon tetrachloride on the total plasma protein concentration of rainbow trout, Salmo gairdneri

Abstract

1. The effect of a single i.p. injection of CCl 4 on total plasma protein and albumin concentrations was measured in the rainbow trout. 2. CCl 4 treatment caused a significant reduction in total plasma protein concentration at 12, 24 and 36 hr post-treatment. 3. At 24 hr post-treatment plasma albumin concentration was significantly reduced only in fish given the highest dose of CCl 4 (2.0 ml/kg). 4. Several factors, including intestinal inflammation and hemorrhages, could have contributed to the decreased plasma protein concentration in the trout.