Abstract
BCAA (isoleucine, leucine and valine) have been reported to enhance food intake and have been used as anti-anorectic agents, especially in critically-ill patients. However, it is not clear whether their stimulatory effect on food intake is the result of an increase in meal size and/or meal number. Furthermore, the impact of individual BCAA on food intake is not well documented. The present experiment was designed to investigate the effect of individual BCAA on meal patterns of rats. Twenty-four adult male Sprague-Dawley rats were randomly divided into four equal groups and fed control diet or diets supplemented with isoleucine, leucine or valine (50 g/kg). Feeding patterns were monitored for 2 weeks using feed recording equipment (model 80350 series; Campden Instruments Limited, Lafayette, IN, USA).
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