Abstract
RESEARCH to date has revealed little or no effect of growth hormone in young chickens, Carter et al. (1955) and Libby et al. (1955). Hsieh et al. (1952) have reported a growth promoting and diabetogenic effect of growth hormone in chick embryos. Guinea pigs and man appear to be insensitive to bovine growth hormone, Selye (1955), while the data of Beck et al. (1957) indicate a slight but significant growth effect of human and monkey growth hormone on a 13-year-old human male. Lack of stimulation by growth hormone may be due to contamination with adrenocorticotrophic hormone, to treatment procedure, to species differences, Wilhelmi (1955) and Knobil (1955), or to “conditioning” of tissue to growth hormone by the adrenal glands, Selye (1955) and Selye and Heuser (1954).The present experiments were designed to test a bovine growth hormone with no adrenocorticotrophic activity detectable at doses up to 4 mg. per 100 …
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