Abstract
PURPOSE: Obesity has been cited in literature to result in variable survival outcomes in critically ill patients. Studies have shown low body mass index (BMI) to be associated with increased mortality in these patients. Effect of BMI on weaning outcomes has received little attention. Obesity can result in increased work of breathing by decreasing thoracoabdominal compliance and causing an abnormal diaphragmatic position. This could result in difficulty in weaning from ventilatory support. The objective of this study was to determine the effect of BMI on weaning and survival outcomes in patients with ventilator-dependent respiratory failure.
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