The effect of body mass index on outcomes following severe blunt chest trauma

Abstract

IntroductionObesity has been described as a significant risk factor for adverse outcomes in hospitalized patients. However, recent literature reports an “obesity paradox”, suggesting that obesity may have a protective effect in a subset of surgical and critically ill patients. The present study assesses the effect of body mass index (BMI) on outcomes following severe isolated blunt chest trauma. MethodsThis was a TQIP database study including patients with severe isolated blunt chest injury (chest AIS 3–5, extrathoracic AIS <3). Patients were excluded for age <20 or >89, death on arrival, facility transfer, or BMI <10 or >55. Patients were divided into five groups according to BMI: underweight (BMI <18.5), normal weight (18.5–24.9), overweight (25.0–29.9), obesity class 1 (30.0–34.9), obesity class 2 (35.0–39.9) and obesity class 3 (≥40.0). Logistic regression models were constructed to evaluate the effect of BMI on outcomes. Results28,820 patients met criteria for inclusion in the analysis. After multivariable analysis, underweight patients as well as obesity class 2 and 3 patients had a significantly higher mortality (OR 1.86 [95% CI, 1.12–3.10], OR 1.48 [95% CI, 1.02–2.16], and OR 1.60 [95% CI, 1.03–2.50]), respectively. Underweight patients had significantly higher risk of overall complications as compared to normal weight patients (OR 1.58 [95% CI, 1.34–1.88]). Obesity class 2 and 3 were independently associated with increased respiratory complications (OR 1.60 [95% CI, 1.27–2.01] and OR 1.58 [95% CI, 1.20–2.09], respectively) and all classes of overweight and obese patients were associated with increased risk of VTE complications (OR 1.68 [95% CI, 1.23–2.27], OR 1.98 [95% CI, 1.42–2.77], OR 2.32 [95% CI, 1.55–3.48], OR 2.02 [95% CI, 1.23–3.33], respectively for overweight and obesity class 1, 2, 3). ConclusionsThe obesity paradox does not extend to severe blunt chest trauma. Underweight and obesity class 2 and 3 patients have worse mortality than normal weight patients. Obesity was independently associated with an increased risk of pulmonary and VTE complications.