The effect of banana peels supplemented diet on acute liver failure rats

Abstract

Peel of vegetables and fruits are of the most important part that helps in protecting the body from diseases, getting rid of the free radicals, as they contain vitamins and minerals which are antioxidant, in addition to phenols. Previous studies have proved the existence of vitamin C, E, and B6 in banana peels, especially vitamin C that can act as an antioxidant.The present study was performed to examine the effect of fresh and dried banana peels consumption on liver function (albumin, GPT, GOT, LDH, GGT and ALP) and lipid profiles cholesterol, triglycerides, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and very low-density lipoprotein (VLDL) on acute liver failure rats induced by carbon tetrachloride. The chemical constituents, vitamins, minerals and fiber were determined for the tested fresh and dried banana peels.This work was carried out on 40 adult male white albino rats randomly classified into eight groups (each of 5 rats). The first group was fed on basal diet as a “negative control”. The other seven groups were injected by carbon tetrachloride to induce liver failure. The second group fed on basal diet as acute liver failure rat’s untreated “positive control”, the third into five groups fed on basal diet containing 5%, 10% and 15% fresh banana peels while the six into eight groups fed on basal diet containing of 5%, 10% and 15% dried banana peels for a period of four consecutive weeks.Results revealed that all acute liver failure groups administrated with different levels of fresh banana peels (5%, 10% and 15%) had significant decrease in liver function, total cholesterol, triglycerides, LDL-c and VLDL-c cholesterol comparing with the positive control group. On the other hand, significant increase in HDL-c was recorded in all acute liver failure groups administrated with dried banana peels 5% and 10% comparing with control positive group. It was suggested that, consumption of fresh and dried banana peels may modify the risk of acute liver failure patients.