Abstract

Summary The haematology of GSH-high and GSH-low type sheep under conditions of anaemia evoked by phlebotomy and kale poisoning was compared. In the early phases of recovery from anaemia red cell GSH concentrations rose in both GSH-high and GSH-low type sheep and this correlated with the appearance of reticulocytes. In the later phases, red cell GSH concentrations in the GSH-high type sheep fell to below normal levels, but in the GSH-low type sheep, values remained higher than normal. The red cells of GSH-low type sheep were more prone to Heinz-body formation than those of GSH-high type sheep. It is suggested that GSH-low type sheep might be more susceptible to anaemia than GSH-high type sheep.

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