Abstract
The aim of the present research is to investigate the effect of an ultra-marathon race on the levels of thyroid, immune and stress system hormones. Moreover, to explore a potential correlation of the above-mentioned hormones with stress hormones.
Highlights
Spartathlon is one of the most difficult and longest running races in the world
C-Reactive Protein (CRP), IL-6, serum Amyloid A (SAA), NTproBNP and cortisol showed a dramatic increase after the race, much higher than their initial values, but returned to their initial equilibrium after 48 hours, except SAA which increased further
A significant correlation was observed in the way cortisol changes with CRP, IL-6 and NTroBNP, which reveals the close relationship of the endocrineimmune system in extreme cases of exercise such as that of Spartathlon
Summary
Spartathlon is one of the most difficult and longest running races in the world. It takes place every year starting from the Acropolis, usually every last Friday of September at 7 in the morning and ends in Sparta in front of the statue of Leonidas at 19:00 of the day, which is the maximum time limit for the race to be completed (< 36 hours). Athletes run on muddy roads and climb on mountains of 1,200 meters altitude without being allowed to rest or sleep, even at night. It is a super-marathon with a fixed distance of 246 km where athletes compete for the best possible time. To explore a potential correlation of the above-mentioned hormones with stress hormones
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