Abstract
Two groups of five male rats each were treated orally (gavage) each day for 14 days. The first group was given amaranth (340 mg/kg/day), the second group was given 0.9% NaCl (the control group). Animals in two other groups were given amaranth intramuscularly (340 mg/kg/day) or 0.9% NaCl (control group) on Days 1, 4, and 11. On Day 14 the effects of the treatments on the activities of the liver and the kidney enzymes (lactate-, malate, glucose-6-phosphate dehydrogenases, glucose-6-phosphatase, and lysosome acid phosphatase) were studied. After po treatment no significant effect could be observed on either the liver or kidney enzymes. After im treatment, however, the activity of the kidney malate dehydrogenase was found to be significantly higher in the amaranth group than in the control group.
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