The Effect of Alpha Antagonists on Pupil Dynamics: Implications for the Diagnosis of Intraoperative Floppy Iris Syndrome

Abstract

Theodossiadis and associates investigated the use of a recent technology to perform quantitative assessment of the pupil dynamics in patients receiving systemic treatment with α1-adrenergic receptor antagonists. 1 Theodossiadis P.G. Achtsidis V. Theodoropoulou S. Tentolouris N. Komninos C. Fountas K.N. The effect of alpha antagonists on pupil dynamics: implications for the diagnosis of intraoperative floppy iris syndrome. Am J Ophthalmol. 2012; 153: 620-626 Abstract Full Text Full Text PDF PubMed Scopus (19) Google Scholar They suggested that preoperative identification of the eyes likely to demonstrate intraoperative floppy iris syndrome (IFIS) should be performed, because it allows “the surgeon to plan and prepare for a more complicated procedure and find potential solution in a timely manner to prevent any postoperative visual disturbances.” In fact, they added that “IFIS might increase the risk of vision-threatening complications.” The Effect of Alpha Antagonists on Pupil Dynamics: Implications for the Diagnosis of Intraoperative Floppy Iris SyndromeAmerican Journal of OphthalmologyVol. 153Issue 4PreviewTo assess pupil dynamics quantitatively in relation to the use of α1-adrenoceptor antagonists, which contribute to the features of intraoperative floppy iris syndrome, using a new, hand-held, digital pupillometer. Full-Text PDF ReplyAmerican Journal of OphthalmologyVol. 154Issue 3PreviewWe thank Carifi and Theoulakis for commenting on our article.1 However, we contend that our research and proposed pupil dynamics assessment can have a clinical impact, especially from medicolegal and ethical perspectives. Full-Text PDF