Abstract
The effects of maternal age, parity, and cigarette smoking on baby weight are reported in 10,692 mothers. Maternal age and parity have no significant effect, but cigarette smoking is associated with a highly significant reduction in baby weight. The effect of smoking is dose-related up to a consumption of 10 to 12 cigarettes per day. Some possible mechanisms of the action of cigarette smoking are reviewed. The adverse effect of increased carboxyhemoglobin in the fetal blood in the earlier months of pregnancy is considered as a possible cause of later retarded fetal growth and development.
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