Abstract
Ventilation and arterial blood gases were measured in ten patients with severe chronic airways obstruction with and without added expiratory obstruction. Added obstruction resulted in a statistically significant decrease in minute ventilation, tidal volume and respiratory frequency. There were no significant changes in alveolar ventilation, arterial blood gases or estimated venous admixture. Oxygen consumption tended to decrease but this was not statistically significant. There was a uniform decrease in physiological dead space indicating some improvement in ventilation perfusion relationships in the lung. The results are compared to those reported during pursed lips breathing.
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