Abstract
The mean number of oocysts per mosquito fed on mice 12 hr after treatment with 100 mg chloroquine/kg was the same level as that in mosquitoes fed on control (untreated) mice despite the fact that no gametocytes were seen in an examination of 10, 000 red blood cells in thin blood films. Though no gametocytes were seen, calculations based on 95% confidence limits from the binomial distribution indicate the possibility of up to 3 gametocytes in a sample of 10, 000 red blood cells. This is equivalent to over 7, 000 gametocytes per blood meal which would appear to be enough to saturate the stomach wall with oocysts.
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