Abstract
Abstract Crosses between various amber mutants of phage λ were carried out in thymine-requiring hosts in growth medium containing thymine or 5-bromouracil (BU). When BU replaced thymine, either in the parental phage DNA and/or in the medium (and presumably therefore in progeny DNA), the fraction of recombinants among the progeny was enhanced several-fold. This enhancement was due, at least in part, to an increase in the number of rounds of mating. A similar enhancement resulted from a period of thymine starvation.
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