Abstract
The uncoupler of aerobic oxidative phosphorylation, 2,4-dinitrophenol (DNP), has been previously shown to decrease the radiation sensitivity of L cells. In the present investigation we performed paired irradiation experiments with DNP-treated cells. Although DNP treatment virtually stops macromolecular synthesis, the paired-dose survival curve showed a definite "repair" segment. The absolute survival reached by the DNP-treated cells was greater than that in parallel irradiated control cells kept in complete growth medium.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
