Abstract
We study 339 patients with acute myocardial infarction (AMI) consecutively treated by primary angioplasty (P-PTCA) patients were divided into diabetes group (63 cases) and non-diabetes group (276 cases). The baseline clinical characteristics, coronary angiogram and major cardiovascular events (MACE) were analysed. No significant differences were observed in coronary artery lesions between the 2 groups. During early follow-up (within 1 month), in diabetes group, left ventricular ejection fraction (LVEF) was lower (0.54±0.10 vs 0.60±0.13, P0.05). At late follow-up (mean 20.6±8.7 months), in diabetes group, the incidence of non-fatal heart failure and rate of target vessel revascularization increased (P0.05). Multivariate analysis indicated the presence of diabetes (RR 4.15, 95% CI:1.29-15.62) and the LVEF were associated with a higher incidence of MACE and they were independent risk factors respectively affecting MACE free survival. MACE free survival rate is lower in AMI patients with than not with diabetes treated by P-PTCA, but overall cardiac mortality rates are similar in the 2 groups, which suggest P-PTCA be more likely to improve the clinical benefit in terms of mortality rate, particularly in diabetes.
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