Abstract
Degeneration is defined as a degradation of tissues and is a substitution in the body of an inferior for a superior form of t issue. Thre e main pointers of degeneration (1) aging (2) disease and (3) injury were identified as the aspects requiring an in - depth study of the role of bio - energies in the process. The Ayurveda texts specifically use the terms Kshaya and Shosha interpreted as atrophy a nd wasting respectively. Dhatu V i kruti, the impairment of the tissues is characteri zed by alteration in the quality of tissue, impairment of function and also complete destruction of the original elements of tissue. An early recognition of Dhatu V ikruti is therefore necessary to help prevent degeneration of the tissue.
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