Abstract
COVID-19 is a new infectious disease, which needs to explore the clinical value of white blood cell count and lymphocyte to provide help for diagnosis and treatment.COVID-19 cases were Selected that admitted to 2 hospitals in Guizhou, China. WBC and LYM in the 1st day, in the 4th day and in the 7th day after onset were collected. There were not any differences in The WBC and LYM in the 4th day and the 7th day between the two groups.WBC and LYM in the 1st day in the moderate group were lesser than in the mild group. WBC and LYM were no dynamic changes in the mild group. In moderate group, WBC and LYM in the 1st day were lesser than in the 4th day. The levels in the 4th day and the 7th day were no differences. The conclusion was In the early stage of COVID-19, the WBC and LYM in moderate patients were significantly decreased within 4 days after onset, and could be restored to normal level after 4-7 days. However, no dynamic changes were observed in mild patients within 7 days.
Highlights
New coronavirus pneumonia(COVID-19) is a new infectious disease with strong infectivity[1]
White blood cell count (WBC) and lymphocyte count (LYM) in the 1st day, the 4th day and the 7th day were no change in the mild group (t=0.755, -1.452, 0.268, 1.577 P>0.05)
This study explored the dynamic changes of WBC and LYM in patients with different degrees of severity and analyzed their clinical significance
Summary
New coronavirus pneumonia(COVID-19) is a new infectious disease with strong infectivity[1]. It is in the midst of a global pandemic. Studies have reported that blood routine examination results showed that WBC and LYM have been reduced in more patients with COVID-19[2, 3]. Testing for WBC and LYM may have important clinical implications for timely diagnosis and assessment of disease severity in patients with COVID-19[4,5,6]. We observed the dynamic changes of WBC and LYM in the early stage of mild COVID-19 and moderate COVID-19, so as to provide help for clinical diagnosis and treatment
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