Abstract
INTRODUCTION Several investigations 1(1–7) have indicated that Pitressin Tannate, an insoluble complex of Pitressin1 and tannic acid, possesses certain advantages over Pitressin and other water-soluble posterior lobe extracts for treatment of diabetes insipidus. The multiple daily injections of antidiuretic hormone necessary with aqueous extracts and attendant disagreeable side reactions encountered with such treatment are eliminated with Pitressin Tannate. Polyuria is controlled by intramuscular injection of Pitressin Tannate in oil at intervals as long as four days. Despite these advantages, communications from physicians and self-treated patients have revealed wide variation in required frequency of treatment in order to maintain satisfactory control over urine volume. These variations were not associated with changing status of the diabetes nor, as shown subsequently, with varying amounts of antidiuretic hormone in the preparations. This communication presents experimental data in hydrated rats showin...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The Journal of clinical endocrinology and metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
