The dual role of manganese oxide simultaneously in enhancing bioactivity and magnetic properties of glass ceramics used in cancer treatment

Abstract

Replacing conventional cancer treatment methods like chemotherapy, which has many adverse effects, with new methods such as magnetic fluid hyperthermia, is one of the significant challenges. In this study, the effect of adding different MnO2 wt% to 20SiO2‐50FeO‐15CaO‐15Na2O glass-ceramic was studied. Maghemite, hematite, jacobsite and sodium calcium silicate phases were crystallized in the glass ceramics. Absorption bands of maghemite with a completely regular crystal structure were observed in the range of 472 and 560 cm−1 wavenumbers. The investigation of the magnetic properties also showed that the saturation magnetization of the samples increased from 21.5 emu/g to 30.80 emu/g by increasing the MnO2 from 0 to 15 wt%. The highest amount of heat loss under alternating magnetic field was also measured for the same sample and its value was 18 °C. Hydroxyapatite with cauliflower morphology was also observed in the phase and structural investigations of the samples immersed in the simulated body fluid.