Abstract
Pituitary fragments and pituitary cell suspensions of the African catfish in a perifusion system released gonadotropic hormone (GTH) spontaneously. After a few hours of perifusion a baseline of GTH release was established. The dopamine (DA) agonist apomorphine (APO) caused a decrease in the release from pituitary fragments but not from pituitary cell suspensions. APO abolished the luteinizing hormone-releasing hormone analog (LH-RHa)-induced GTH release from both pituitary fragments and cell suspensions. It was concluded that DA inhibits the GTH release induced by gonadotropin-releasing hormone.
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