Abstract

The Diversity in Dust Fungal Spores Concentration at Four Districts of Al-Najaf Environment and their Potential Correlation with Asthma

Highlights

  • Asthma can be defined as a complex inflammatory disease of the airway, Characterized by bronchial hyperplasia

  • The result of this study revealed the highest fungal spore concentration was in the dust of Kufa district (29%), the most prevalent fungal isolate from the dust belonged to the genus Aspergillus, Alternaria, Cladosporium, and Penicillium

  • The highest log-fungal spore concentration was in March (8.4456 CFU\g ), there were three other peaks found in April, October and November with (8.2949, 8.206, 8.0212 CFU\g) respectively, while the lowest log- fungal spore concentration was recorded in January (7.1717 CFU\g)

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Summary

Introduction

Asthma can be defined as a complex inflammatory disease of the airway, Characterized by bronchial hyperplasia. Several family studies estimated that genetic factors have a relative contribution with atopic and asthma, it is possible to reach 40%-60%. While further studies conducted that asthma was not just a genetic disease but it was a disease result from the interaction of multiple genetic and environmental factors[1]. Filamentous fungi are common aeroallergens patients represented a major part of the bioaerosol, it was called molds which consist mainly of three phyla; Zygomycota, Ascomycota, and Deutromycota. Phyla of these molds have different way of reproduction; each species have the ability to make several kinds of spores that could be sexual and asexual. Enormous correlative evidence proposes an association between fungi and asthma, that may be triggered from the elevated in the numbers of airborne fungal spores[5,6]

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