Abstract
The distribution of methionine-enkephalin, serotonin and β-lipotropin-containing neurones has been mapped immunohistochemically in the brainstem of the cat after local colchicine injections. Serotonin-containing neurones were found in the raphe in nucleus raphe magnus (NRM), nucleus raphe pallidus (NRP) and nucleus raphe obscurus (NRO) and in a band extending across the ventral reticular formation into nucleus paragigantocellularis lateralis (PGL) and nucleus lateralis reticularis (LRM). Enkephalin-positive cell bodies were also found in these raphe nuclei and in most divisions of the caudal reticular formation. Double labelling studies established that enkephalin and serotonin co-exist within some neurones in NRM and NRP, β-Lipotropin-positive cell bodies were found principally within NRP and within the ventrolateral reticular formation in PGL and LRM.
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