Abstract
The frequencies of 21 HL‐A antigens were studied in an indigenous population of 247 people from the coastal regions of Papua New Guinea and the surrounding islands. The antigens HL‐A9,10,11 (first series) and HL‐A13, W10, W22 (second series) occurred with high frequencies. Twelve of the 21 antigens were either not found or occurred with a frequency of less than 10%. The population studied was classified into 12 Administrative Districts according to birthplace. Variations in antigen frequencies were noted between the different Districts. This variation can be attributed to random genetic drift, gene flow from other ethnic groups, or a combination of both. The genetic distance between three of the Districts (Milne Bay, Central, and Gulf) were calculated. These results were consistent with the geographic relationship of the three Districts.
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