Abstract
Candida albicans is a pathogenic yeast typically associated with diseases such as HIV, AIDS, and other immunocompromised conditions. It is rarely the cause of fatalities and is commonly treated with drugs administered orally or intravenously. In this experiment, Candida albicans was tested with an extract of modified hydrothermal nanotitania to identify whether the material is capable of inhibiting the organism’s growth. The extract was mixed with the Candida albicans in a culture media preparation to determine whether the organisms were able to grow. The test showed that modified hydrothermal nanotitania inhibits the growth of this organism.
Highlights
A fungus is a common single-celled or eukaryotic organism
Modified hydrothermal nanotitania extract containing titanium dioxide (TiO2) mixed with 0.01%, 0.03%, and 0.05% silver nanoparticles and “titanium dioxide only” is more capable of stopping the growth of Candida albicans than the control media
Titanium dioxide (TiO2) comprising silver concentrations at various percentages (0.01%, 0.03%, and 0.05%) and TiO2 only are able to inhibit the growth of Candida albicans on an agar plate in comparison to a control containing no nanoparticles
Summary
The most commonly found dimorphic type is Candida albicans. It frequently causes various local medical infections of the nails, vagina (vaginitis), and respiratory system. Candida infection or candidosis rarely occurs spontaneously as it needs favourable conditions for growth. Those patients most prone to developing candidosis are those receiving broad-spectrum antibiotics and those with diabetes mellitus. In these groups, candida develops in the saliva [1]. Candidosis may be preceded by a fever of unknown origin leading to systemic fungal infection [2]
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