Abstract
Beginning in the early eighteenth century, biologists and physicists alike strove to find a link between electricity and nervous function. Luigi Galvani took the first step by demonstrating the presence of electricity in animal tissues. Over the next half-century, others went on to show that nerve and muscle tissues generate electrical transients that accompany excitation, but the lack of sensitive instruments hampered these studies. Julius Bernstein, with the help of Emil du Bois-Reymond, found a way to overcome these technical limitations and in about 1865 made the first recordings of the time course of the action potential.
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