Abstract
A digital structural analysis method with the aid of a scanning densitometer was successfully applied to paracrystalline inclusion bodies which have been found in the brains of humans exhibiting senile dementia. Based on Fourier techniques involving noise removal and enhancement for structural analysis from a computer-generated diffractogram, it is proposed that the crystalline bodies from thin sections of the specimen constitute a stranded helix of 18.5 nm pitch. From the digital processed data obtained from the various different electron micrographs obtained by the use of a tilting device, a three-dimensional model and Fourier synthetic images representing the precise arrangement of the Hirano body stranded helix are derived and graphically demonstrated.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
