The diffusion of potassium, sodium, sucrose and inulin in the extracellular spaces of mammalian tissues

Abstract

The diffusion of K, previously reported to be low in the extracellular fluid of mammalian muscle, has been shown to be slowed also in the extracellular space of brain tissue; whereas in liver K diffuses at about the free solution rate. Diffusion constants have been estimated for Na ions, inulin and sucrose in these three tissues, and are all approximately at the free solution level. In peripheral nerve the diffusion of all test substances is low, possibly due to the epineureum.