Abstract

The diagnostic- difficulties that may be encountered in infectious mononucleosis were impressively denKmsjtr'abed to us in a series of 106 patients with this disease, in whom complete clinical data were available. In 63 of these patients, prior to availability of hematologic and serologic findings, 26 diseases other than infec­ tious mononucleosis were diagnosed: agranulocytosis, appendicitis, brucellosis, diphtheria, duodenal ulcer, gastro-enteritis, Hodgkin's disease, infectious hepa­ titis, influenza, leukemia, measles, meningitis, nephritis, pharyngitis, ulcerative pharyngitis, pneumonia, virus pneumonia, purpura, scarlet fever, serum disease, frontal sinusitis, streptococcic sore throat, acute follicular tonsillitis, acute ulcera­ tive tonsillitis, tuberculous lymphadenitis, Vincent's angina. According to the experience of other authors, the following 23 additional erroneous diagnoses have been recorded in the literature: angioneurotic edema, asthma, bacterial endocardi­ tis, chickenpox, encephalitis, erysipelas, erythema multiforme, erythema nodosum, edema of glottis, hyperthyroidism with lymphocytosis, infectious lympho­ cytosis, myocarditis, mumps, obstructive jaundice, poliomyelitis, acute rheu­ matic fever, rickettsialpox, stomatitis, syphilitic cervical adenitis, secondary

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