Abstract
SARS-CoV-2 is a novel virus from the coronavirus family that emerged in the end of December 2019 in Wuhan, China. The virus is now widespread and causing the current pandemic of COVID-19, a highly pathogenic viral pneumonia, commonly presented with fever and cough, which frequently lead to lower respiratory tract disease with poor clinical outcomes associated with older age and underlying health conditions. Supportive care for patients is typically the standard protocol because no specific effective antiviral therapies have been identified so far. The current outbreak is challenging governments and health authorities all over the world. In here we present a comparison among the current diagnostic tools and kits being used to test Brazilian population.
Highlights
The coronavirus disease 2019 (COVID-19) epidemic started in December 2019, in Wuhan, Hubei province, in China
SARS was initiated by zoonotic transmission of a novel coronavirus in markets in Guangdong province, China
COVID-19 is a novel disease caused by a novel coronavirus (SARS-CoV-2) that emerged in 2019 that is challenging scientists all over the world since its appearance
Summary
The coronavirus disease 2019 (COVID-19) epidemic started in December 2019, in Wuhan, Hubei province, in China. The manufacturer of the test Anti COVID-19 IgG/ IgM Rapid Test declared that no false results were observed in positive sample for the pathogens: influenza A, influenza BRSV, adenovirus, HBsAg syphilis, Helicobacter pylori, HIV and HCV This kind of assay shows some advantages such as: it is an established mature technology; relative ease of manufacture since equipment and processes are already developed and available; scalable to high volume production, stable, since shelf-lives varies from 12 to 24 months often without refrigeration; ease of use; relatively low cost and short timeline for development and approval (O’Farrell, 2009). Broad-range PCR attempt to detect a broader group of organisms by designing primers that are complementary to conserved regions of a particular gene that are shared by a given taxonomic group (Relman, 1998) Another variation is multiplexing, in which multiple specific PCR assays are run simultaneously in the same reaction tube test for multiple different DNA templates.
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