Abstract

The differences in water suppressed VOSY of the brain between a live and dead mouse have been observed in experiments. In the water suppressed VOSY of the dead mouse brain some spectral lines near the water signal have disappeared but these spectral lines do exist in the water suppressed VOSY of the live mouse brain. The approach used to obtain the water suppressed VOSY of the mouse brain is termed phase-shift presaturation, whose water suppression factor, tested by a phantom of an aqueous solution of ethanol, is greater than 1000.

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