The diagnostic value of Superb Microvascular Imaging in identifying benign tumors of parotid gland

Lihui Zhao,Yiran Mao,Jing Zhao,Jie Mu,Sheng Zhang,Xiaojie Xin,Fangxuan Li

doi:10.1186/s12880-020-00506-y

Abstract

BackgroundWe compared the ultrasound features, superb microvascular imaging (SMI) and micro vessel density (MVD) of pleomorphic adenoma (PA), Warthin’s tumor (WT) and basal cell adenoma (BCA) to explore the clinic value of SMI in differential diagnosis of benign tumors of parotid gland.MethodsThe vascular distributions and grade by color doppler flow imaging (CDFI) and SMI, as well as vascular index (VI) of 249 parotid gland masses from 217 patients were analyzed.ResultsThe internal echogenicity of BCA are more homogeneous in comparing with WT and PA(P < 0.05). By SMI, the vascular distribution and vascular grade in PA were mainly peripheral (33.1%) and avascular (25.7%), Grade 1 (27.8%) and Grade 0 (25.7%). WT were mainly central (31.3%) and mixed distribution (34.9%), in Grade 3 (37.3%) and Grade 2 (36.2%). BCA was mainly peripheral (33.3%) and mixed distribution (33.3%), in Grade 2 (33.3%) and Grade 3 (33.3%). The overall detection rate of SMI for vascular Grade 2 and 3 was significantly higher than that of CDFI (P < 0.05). Both VI and MVD were lowest in PA, highest in WT (P < 0.001). The VI by SMI was correlated with MVD (P < 0.001). The correlation index between vascular distribution and grade by SMI and MVD were significantly higher than CDFI.ConclusionSMI can provide low-velocity blood flow information, which is helpful for the differential diagnosis of common benign tumors of parotid gland, and is expected to be more widely used.

Highlights

We compared the ultrasound features, superb microvascular imaging (SMI) and micro vessel density (MVD) of pleomorphic adenoma (PA), Warthin’s tumor (WT) and basal cell adenoma (BCA) to explore the clinic value of SMI in differential diagnosis of benign tumors of parotid gland
SMI can provide low-velocity blood flow information, which is helpful for the differential diagnosis of common benign tumors of parotid gland, and is expected to be more widely used
Parotid gland tumors account for 3–6% of head and neck tumors [1]. 80% parotid gland tumors are benign tumors, in which pleomorphic adenoma (PA), Warthin’s tumor (WT) and basal cell adenoma (BCA) account for the top three [2]

Summary

Introduction

We compared the ultrasound features, superb microvascular imaging (SMI) and micro vessel density (MVD) of pleomorphic adenoma (PA), Warthin’s tumor (WT) and basal cell adenoma (BCA) to explore the clinic value of SMI in differential diagnosis of benign tumors of parotid gland. Parotid gland tumors account for 3–6% of head and neck tumors [1]. 80% parotid gland tumors are benign tumors, in which pleomorphic adenoma (PA), Warthin’s tumor (WT) and basal cell adenoma (BCA) account for the top three [2]. Different types of parotid gland tumors have different biological behaviors; different. Basal cell adenoma was first reported by Kleinsasser and Klein in 1967, until 1991 it was first time that the WHO classified basal cell adenoma (BCA) as a independent solid tumor type. BCA is not rare in clinic, while the misdiagnosis rate for BCA is as high as 50% [3]

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