Abstract
According to the definition of chronic respiratory diseases (CRD) by the World Health Organization, CRD is a group of diseases that affect the airways and other structures of the lungs, the most common include COPD, bronchial asthma, bronchiectasis, etc..
Highlights
According to the definition of chronic respiratory diseases (CRD) by the World Health Organization, CRD is a group of diseases that affect the airways and other structures of the lungs, the most common include COPD, bronchial asthma, bronchiectasis, etc. [1]
This study confirmed that patients with pulmonary aspergillosis had more chronic respiratory diseases in the case group than in the control group,PTB (82.6 vs.20.0%,P=0.001),COPD (43.5% vs.22.0%,P=0.025),which was consistent with the results reported in literature [6].The early clinical manifestations of pulmonary aspergillosis are not specific, and the typical chest CT findings are often related to the time of disease occurrence and the severity of lesion development, and the imaging findings cannot lead to a definite etiological diagnosis
Through ROC curve analysis, the AUROC of Bronchoalveolar lavage fluid (BALF) GM test was 0.779(95%CI:0.684-0.874).When BALF GM test limit> 0.96,Sen was 67.4%,Spe was 78.0%,positive predictive value (PPV) was 73.8%, negative predictive value (NPV) was 72.2%, PLR was 3.06.When serum GM limit was greater than 0.18,AUROC was the highest, Sen was 45.5%,Spe was 83.3%,and P=0.255.The purpose of this study was to understand the value of BALF GM in the early diagnosis of pulmonary aspergillosis in patients with nonneutropenia complicated with pulmonary underlying diseases
Summary
According to the definition of chronic respiratory diseases (CRD) by the World Health Organization, CRD is a group of diseases that affect the airways and other structures of the lungs, the most common include COPD, bronchial asthma, bronchiectasis, etc. [1]. According to the definition of chronic respiratory diseases (CRD) by the World Health Organization, CRD is a group of diseases that affect the airways and other structures of the lungs, the most common include COPD, bronchial asthma, bronchiectasis, etc. In-depth studies in recent years have found that pulmonary aspergillosis can occur in patients with chronic respiratory diseases (CRD) [2,3]. GM can be detected in the blood in the early stages of infection. Various factors have been found in clinical practice to cause false positives and false negatives in galactomannan testing. Bronchoalveolar lavage fluid (BALF) can be applied to detect pathogens on lung lesions in the early stage of aspergillus infection. To evaluate the diagnostic value of galactomannan testing in bronchoalveolar lavage fluid on the diagnosis of pulmonary aspergillosis in patients with chronic respiratory diseases
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Biomedical Journal of Scientific & Technical Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
